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Cat No. | Product Name | Synonyms | Targets |
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T79256 | DPP-4-IN-8 | ||
DPP-4-IN-8 (compound 27) is a potent and selective inhibitor of dipeptidyl peptidase 4 (DPP4), with an inhibition constant (Ki) of 0.96 μM. It inhibits the dipeptidase activity of DPP4 in both Caco-2 and HepG-2 cells and... | |||
T77080 | Manfidokimab | ||
Manfidokimab (AK120), an IgG4 monoclonal antibody targeting the interleukin 4 receptor alpha (IL-4Rα), demonstrates therapeutic efficacy as detailed in reference [1]. | |||
T77036 | Inolimomab | ||
Inolimomab, an anti-interleukin-2 receptor (IL-2R) α chain monoclonal antibody, has demonstrated potential to enhance survival rates in preliminary studies addressing acute graft-versus-host disease (aGVHD) [1] [2]. | |||
T78508 | Delmitide acetate | RDP-58 acetate | IFNAR |
Delmitide acetate (RDP58) is an orally active d-isomer decapeptide that exhibits potent anti-inflammatory properties. This compound suppresses the production of TNF-α, IFN-γ, and interleukin (IL)-12, while enhancing the ... | |||
T80854 | Vopikitug | ||
Vopikitug, a human IgG1-kappa monoclonal antibody targeting the IL2RA (interleukin 2 receptor alpha subunit, IL-2RA, TAC, p55, CD25), exhibits antineoplastic activity [1]. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6S1597 | Mulberroside A | TNF , Tyrosinase , Interleukin | |
1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of... | |||
T6S1579 | Monotropein | Monotropeine | Others |
1. Monotropein (Monotropeine) has antinociceptive action. 2. Monotropein has anti-apoptosis and anti-catabolic activity in chondrocytes. 3. Monotropein has anti-inflammatory action by inhibition of the expressions of inf... | |||
T2S2264 | Linalool | Linalol,(±)-Linalool,Phantol | Apoptosis , IL Receptor , TNF , Endogenous Metabolite , iGluR |
1. Linalool (Linalol), a natural compound of the essential oils, has been shown to have antinociceptive, antimicrobial, and anti-inflammatory properties. 2. Linalool was protected against LPS/GalN-induced liver injury th... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01738 | IL-1 alpha/IL-1A Protein, Mouse, Recombinant | Mouse | E. coli |
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli... | |||
TMPY-00437 | IL-11R alpha chain 1/IL-11RA1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
IL-11R alpha chain 1/IL-11RA1 Protein, Rat, Recombinant (His) is expressed in HEK293 cells. | |||
TMPJ-00162 | IL-1 alpha/IL-1A Protein, Human, Recombinant (hFc) | Human | Human Cells |
Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately ... | |||
TMPY-00854 | IL-1 alpha/IL-1A Protein, Human, Recombinant | Human | HEK293 |
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli... | |||
TMPY-06981 | IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli) | Human | E. coli |
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli... | |||
TMPY-01258 | IL-13RA1 Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,... | |||
TMPY-01170 | IL-13RA1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,... | |||
TMPY-00856 | TCCR Protein, Human, Recombinant (hFc) | Human | HEK293 |
The interleukin-27 receptor is a type I cytokine receptor for interleukin-27. It is a heterodimer composed of the interleukin 27 receptor, alpha subunit, and glycoprotein 130. WSX-1/IL-27R, a class I cytokine receptor th... | |||
TMPY-02879 | IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158) | Human | E. coli |
Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine that plays an important role in innate and adaptive immunity. IL-1F6 activates MAPK and NF-kB pathways a... | |||
TMPY-01047 | IL-1R1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Interleukin 1 receptor, type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family. This pro... | |||
TMPY-01250 | IL-11R alpha/IL-11RA Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, includi... | |||
TMPY-05836 | IL-1 alpha/IL-1A Protein, Rat, Recombinant | Rat | E. coli |
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli... | |||
TMPY-02994 | IL-13RA1 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,... | |||
TMPY-04287 | IL-22RA1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
IL-22R belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains and is expressed in the colon, liver, lung, pancreas, and kidney. IL-22R also can be expressed in keratinocytes of normal... | |||
TMPY-06519 | IL-13RA1 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 |
Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,... | |||
TMPY-04286 | IL-22RA1 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
IL-22R belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains and is expressed in the colon, liver, lung, pancreas, and kidney. IL-22R also can be expressed in keratinocytes of normal... | |||
TMPY-04087 | IL-22RA1 Protein, Canine, Recombinant (His) | Canine | HEK293 |
IL-22R belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains and is expressed in the colon, liver, lung, pancreas, and kidney. IL-22R also can be expressed in keratinocytes of normal... | |||
TMPY-04816 | IL-13RA1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,... | |||
TMPY-04002 | IL-22RA1 Protein, Canine, Recombinant (hFc) | Canine | HEK293 |
IL-22R belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains and is expressed in the colon, liver, lung, pancreas, and kidney. IL-22R also can be expressed in keratinocytes of normal... | |||
TMPJ-00161 | IL-1 alpha/IL-1A Protein, Human, Recombinant (Avi), Biotinylated | Human | E. coli |
Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately ... | |||
TMPK-00920 | IL-1 alpha/IL-1A Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and b... | |||
TMPY-00592 | IL-3R alpha/CD123 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf... | |||
TMPY-06590 | IL-13RA1 Protein, Human, Recombinant (aa 1-343, hFc) | Human | HEK293 |
Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,... | |||
TMPY-00076 | IL-3R alpha/CD123 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf... | |||
TMPY-06579 | IL-13RA1 Protein, Human, Recombinant(aa 1-343, His & Avi), Biotinylated | Human | HEK293 |
Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,... | |||
TMPY-01074 | IL-13RA1 Protein, Human, Recombinant (His & hFc) | Human | HEK293 |
Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,... | |||
TMPY-05123 | IL-13RA1 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,... | |||
TMPJ-00270 | IL-13RA1 Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | Human Cells |
Interleukin-13 receptor subunit alpha-1(IL-13RA1), also known as NR4, belongs to the hemopoietin receptor family. Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. It interacts with TR... | |||
TMPY-06792 | TCCR Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | HEK293 |
The interleukin-27 receptor is a type I cytokine receptor for interleukin-27. It is a heterodimer composed of the interleukin 27 receptor, alpha subunit, and glycoprotein 130. WSX-1/IL-27R, a class I cytokine receptor th... | |||
TMPY-05543 | TCCR Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The interleukin-27 receptor is a type I cytokine receptor for interleukin-27. It is a heterodimer composed of the interleukin 27 receptor, alpha subunit, and glycoprotein 130. WSX-1/IL-27R, a class I cytokine receptor th... | |||
TMPY-05432 | IL-13RA1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,... | |||
TMPY-05795 | IL-13RA1 Protein, Mouse, Recombinant (mFc) | Mouse | HEK293 |
Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,... | |||
TMPJ-01424 | IL-10R alpha/IL-10RA Protein, Macaca mulatta, Recombinant (His) | Macaca Mulatta | Human Cells |
Interleukin-10 Receptor alpha (IL-10 R alpha), also known as IL-10 R1, is transmembrane glycoprotein member of the class II cytokine receptor family. Interleukin-10 (IL10) is a key anti-inflammatory cytokine that is prod... | |||
TMPY-01956 | IL-36 alpha/IL-1F6 Protein, Mouse, Recombinant | Mouse | E. coli |
Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine that plays an important role in innate and adaptive immunity. IL-1F6 activates MAPK and NF-kB pathways a... | |||
TMPJ-00291 | IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated | Human | Human Cells |
Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. IL6Ra is a part of the receptor for interleukin 6 cytokine. IL6Ra binds to... | |||
TMPJ-00119 | IL-22RA2 Protein, Human, Recombinant (hFc) | Human | Human Cells |
Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. I... | |||
TMPY-02818 | IL-36 alpha/IL-1F6 Protein, Human, Recombinant (His) | Human | E. coli |
Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine that plays an important role in innate and adaptive immunity. IL-1F6 activates MAPK and NF-kB pathways a... | |||
TMPY-03426 | IL-1R1 Protein, Human, Recombinant | Human | HEK293 |
Interleukin 1 receptor, type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family. This pro... | |||
TMPY-01048 | IL-1R1 Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin 1 receptor, type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family. This pro... | |||
TMPJ-00850 | ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) | Mouse | Human Cells |
ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes.... | |||
TMPY-03273 | IL-18 Protein, Mouse, Recombinant | Mouse | E. coli |
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-g... | |||
TMPY-00277 | IL-18 Protein, Human, Recombinant | Human | E. coli |
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-g... | |||
TMPJ-00051 | IL-3 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit... | |||
TMPY-01928 | IL-18 Protein, Rhesus, Recombinant (His) | Rhesus | E. coli |
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-g... | |||
TMPY-02549 | GBP1 Protein, Human, Recombinant (His) | Human | HEK293 |
Guanylate-binding protein 1 (GBP-1) is a member of the GBP family whose members are GTPases induced in response to interferon-λ (IFN-λ), with seven highly homologous members in humans, termed HuGBP-1 to HuGBP-7. GBP-1 ex... | |||
TMPJ-00849 | ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc) | Mouse | Human Cells |
ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes.... | |||
TMPJ-00177 | BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated | Human | Human Cells |
B-cell activating factor (BAFF), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a transmembrane glycoprotein in the TNF ligand superfamily. BAFF is a cytokine and serves as a ligand for receptors TNFRSF13B (TACI), T... | |||
TMPY-05353 | CCL26 Protein, Human, Recombinant | Human | Baculovirus-Insect Cells |
The eotaxin subfamily of CC chemokines consists of eotaxin-1/CCL11, eotaxin-2/CCL24 and eotaxin-3/CCL26. All eotaxins induce the trafficking of eosinophils to the sites of inflammation via CC chemokine receptor 3 (CCR3),... | |||
TMPY-03381 | IL-18 Protein, Human, Recombinant (GST) | Human | E. coli |
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-g... | |||
TMPY-04451 | AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus-Insect Cells | |||
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Cat No. | Product Name | ||
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L9840 | Anti-Alzheimer's Disease Compound Library | 986 compounds | |
A unique collection of 986 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS. |